MECHANISM

Targets the Neuro-Immune-Cutaneous (NIC) system, addressing sensitive skin the root: – Neuro Soothing: Reduces Ca²⁺ concentration & inhibits CGRP in neuronal cells, effectively reducing pain, itching and feelings of discomfort. – Immuno Soothing: Suppresses pro-inflammatory cytokines (TNF-α, IL-1β, IL-8), NF-κB signaling, and IgE production, rebalancing the skin immune system for enhanced protection against external stimuli – Cutaneous Soothing: Selectively inhibits pathogenic bacteria (S. aureus, C. acnes IA1), regulates skin microbiome and pH, activates skin receptors, and supports collagen synthesis, reinforcing multilayer barrier integrity across microbial, chemical, physical and biological aspects